Take bus 100 to the last stop, Metro Station (Line B – Yellow Line). Take the underground metro to Karlovo náměstí. Exit the metro and follow signs to Karlovo náměstí (not towards Palackého náměstí). After the escalator, take EXIT SPÁLENÁ up the stairs to street-level and turn left. Walk to the end of the block and take another left onto Odbor Street (beside the Sony store). At the end of the street you will see MOOo white historical building at Myslíkova 22.
Exit the train station and walk through the park, cross the street and make a right to Jeruzalémská, walk down the street (pass a synagogue). get on tram number 5 in the direction of Barrandov (tram goes through Wenceslas Square). Get off at Myslíkova (4 stops) and cross the street. At the end of the street you will see MOOo building.